Vitamin K

Vitamin K2 is a fat-soluble vitamin that plays a crucial role in various physiological processes, particularly in the regulation of blood clotting and bone metabolism. The history of vitamin K2 is closely linked to the broader history of vitamin K.

The discovery of vitamin K dates back to the early 20th century. In 1929, Danish researcher Henrik Dam, along with his colleague Edward Adelbert Doisy, identified a substance that was essential for blood coagulation in chickens. They initially called it "coagulation vitamin," which was later renamed vitamin K, with the 'K' derived from the German word "Koagulationsvitamin."

It wasn't until the 1930s that scientists recognized there were different forms of vitamin K, namely vitamin K1 (phylloquinone) and vitamin K2 (menaquinone). The primary dietary source of vitamin K1 is green leafy vegetables, while vitamin K2 is found in fermented foods, some animal products, and produced by bacteria in the human gut.

The distinct forms of vitamin K2, such as menaquinone-4 (MK-4) and menaquinone-7 (MK-7), have gained attention for their unique roles in health. MK-4 is found in animal products, while MK-7 is produced by bacteria during the fermentation of certain foods.

In the following decades, research expanded to explore the diverse functions of vitamin K2 beyond its established role in blood clotting. In the 1970s and 1980s, Japanese researcher Dr. Tetsuo Sato made significant contributions to understanding the importance of vitamin K2, particularly MK-4, in bone health. His research showed that MK-4 played a crucial role in regulating bone metabolism and preventing osteoporosis.

As interest in vitamin K2 grew, more studies highlighted its potential benefits in cardiovascular health and other areas. The recognition of its role in directing calcium to the bones and teeth, while preventing its accumulation in arteries and soft tissues, has contributed to the understanding of its importance in overall health.

Today, vitamin K2 continues to be an area of active research, with ongoing studies exploring its potential therapeutic applications in bone health, cardiovascular health, and beyond. The understanding of this vitamin's diverse functions underscores its significance in maintaining optimal health.